My husband Daniel's 6th great grandfather, Sebastian Truckenmiller, came to America in 1732. He married, and had 8 children. My husband is descended from Sebastian's youngest son, Jacob.
Sebastian's second son, George, married Susanna Lohr. Although it's not the only time Truckenmiller was written as Druckenmiller, George's children all appear to use the Druckenmiller spelling.
Although there are other Druckenmiller and Truckenmiller lines that came to America at later dates, and there are other times that Truckenmiller was spelled Druckenmiller (or Druckenmueler) many Druckenmiller's in our area can trace their line back to George Truckenmiller, son of immigrant Sebastian Truckenmiller.
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More about Sebastian Truckenmiller - http://heathersgen.blogspot.com/2013/09/johan-sebastian-truckenmiller-1715-1795.html
More on Michael Druckenmiller 1784-1846 here - http://notheathersgen.blogspot.com/2012/05/michael-druckenmiller-1784-1846.html
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From Floyd's History Of North'd County -
"The family has become numerous in eastern and central Pennsylvania, and the name is often found corrupted into Druckenmiller, the Berks county branch spelling it so. The ancestor of the Northumberland family, Sebastian Truckenmiller, spelled it with a "T," however, and that seems to be the correct form. Sebastian Truckenmiller came to America on the pink "John and William," of Sunderland, Constable Tymperton, master, from Rotterdam,
which qualified at Philadelphia Oct. 17, 1732. On the original list of passengers (Pennsylvania Archives, Vol. XVII, Second Series, pages 72- 73)"
and later -
"As previously mentioned, some branches of the family spell the name
Druckenmiller. Of these, Michael Druckenmiller, millwright, of Herefordtownship, Berks county, was said to be a descendant of the Charles
Truckenmiller who in 1790 lived in Hereford township. Michael's children
were: Daniel, Enos, Clara, Hannah, Lucy and Elizabeth.
Enos Druckenmiller (as he wrote his name), son of Michael, was born
Dec. 14, 1821, and died March 29, 1899, at Zieglersville in Upper
Milford township, Lehigh Co., Pa., his death being caused by apoplexy.
He is buried in the Lutheran cemetery at that place, and was long an
active worker in the church, in all its departments; serving as elder
and Sunday school teacher. He was a member of the building committee
when the new church was erected. For many years he was director of a
singing school. Mr. Druckenmiller was a prosperous farmer and mechanic
all his life, owning several farms.: